Ultra-rapid somatic variant detection via real-time targeted amplicon sequencing

Ultra-rapid somatic variant detection via real-time targeted amplicon sequencing

A method for detection of somatic variants is presented for the intraoperative evaluation of tumor mutations in less than 30 min, using rapid DNA extraction, in silico optimized LAMP amplification, and a LAMP product analysis tool: LAMPrey.

Bibliographic Details
Main Authors: Jack Wadden, Brandon S. Newell, Joshua Bugbee, Vishal John, Amy K. Bruzek, Robert P. Dickson, Carl Koschmann, David Blaauw, Satish Narayanasamy, Reetuparna Das
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03657-6

Internet

https://doi.org/10.1038/s42003-022-03657-6

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