HER2-Targeted Therapy—From Pathophysiology to Clinical Manifestation: A Narrative Review

Trastuzumab is the primary treatment for all stages of HER2-overexpressing breast cancer in patients. Though discovered over 20 years ago, trastuzumab-induced cardiotoxicity (TIC) remains a research topic in cardio-oncology. This review explores the pathophysiological basis of TIC and its clinical m...

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Bibliographic Details
Main Authors: Svetoslava Elefterova Slavcheva, Atanas Angelov
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:https://www.mdpi.com/2308-3425/10/12/489