Multifunctional profiling of triple-negative breast cancer patient-derived tumoroids for disease modeling

Multifunctional profiling of triple-negative breast cancer patient-derived tumoroids for disease modeling

3D cell models derived from patient tumors are highly translational tools that can recapitulate the complex genetic and molecular compositions of solid cancers and accelerate identification of drug targets and drug testing. However, the complexity of performing assays with such models remains a hurd...

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Bibliographic Details
Main Authors: Evan F Cromwell, Oksana Sirenko, Ekaterina Nikolov, Matthew Hammer, Courtney K Brock, Margarite D Matossian, Madlin S Alzoubi, Bridgette M Collins-Burow, Matthew E Burow
Format: Article
Language:English
Published: Elsevier 2022-04-01
Series:SLAS Discovery
Subjects:
Microfluidics
Tumoroids
High-content Imaging
Metabolism
Patient-derived
Disease modeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2472555222000119

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http://www.sciencedirect.com/science/article/pii/S2472555222000119

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