Allosteric modulators of solute carrier function: a theoretical framework

Large-scale drug screening is currently the basis for the identification of new chemical entities. This is a rather laborious approach, because a large number of compounds must be tested to cover the chemical space in an unbiased fashion. However, the structures of targetable proteins have become in...

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Bibliographic Details
Main Authors: D. Boytsov, K. Schicker, E. Hellsberg, M. Freissmuth, W. Sandtner
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Physiology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2023.1166450/full