13C tracer analysis suggests extensive recycling of endogenous CO2 in vivo

Abstract Background 13C tracer analysis is increasingly used to monitor cellular metabolism in vivo and in intact cells, but data interpretation is still the key element to unveil the complexity of metabolic activities. The distinct 13C labeling patterns (e.g., M + 1 species in vivo but not in vitro...

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Bibliographic Details
Main Authors: Likun Duan, Daniel E. Cooper, Grace Scheidemantle, Jason W. Locasale, David G. Kirsch, Xiaojing Liu
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Cancer & Metabolism
Subjects:
Online Access:https://doi.org/10.1186/s40170-022-00287-8