Unveiling Metabolic Vulnerability and Plasticity of Human Osteosarcoma Stem and Differentiated Cells to Improve Cancer Therapy

Unveiling Metabolic Vulnerability and Plasticity of Human Osteosarcoma Stem and Differentiated Cells to Improve Cancer Therapy

Defining the metabolic phenotypes of cancer-initiating cells or cancer stem cells and of their differentiated counterparts might provide fundamental knowledge for improving or developing more effective therapies. In this context we extensively characterized the metabolic profiles of two osteosarcoma...

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Bibliographic Details
Main Authors: Gerardo Della Sala, Consiglia Pacelli, Francesca Agriesti, Ilaria Laurenzana, Francesco Tucci, Mirko Tamma, Nazzareno Capitanio, Claudia Piccoli
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Biomedicines
Subjects:
oncometabolism
cancer stem cell
metabolic therapy
mitochondria
cisplatin
osteosarcoma
Online Access:https://www.mdpi.com/2227-9059/10/1/28

Internet

https://www.mdpi.com/2227-9059/10/1/28

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