Bioengineering of <i>Escherichia coli Nissle 1917</i> for Production and Excretion of Spermidine, a Key Metabolite in Human Health

Bioengineering of <i>Escherichia coli Nissle 1917</i> for Production and Excretion of Spermidine, a Key Metabolite in Human Health

Microbiota-derived metabolites have biological importance for their host. Spermidine, a metabolite described for its protective effect in age-related diseases, is now studied for its role in the resolution of inflammation and gut homeostasis. Strategies to modulate its production in the gastrointest...

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Bibliographic Details
Main Authors: Clément Caffaratti, Caroline Plazy, Valérie Cunin, Bertrand Toussaint, Audrey Le Gouellec
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Metabolites
Subjects:
microbiota
immunity
spermidine
metabolic engineering
probiotics
Live Biotherapeutic Product
Online Access:https://www.mdpi.com/2218-1989/12/11/1061

Internet

https://www.mdpi.com/2218-1989/12/11/1061

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