Dietary plant stanol ester supplementation reduces peripheral symptoms in a mouse model of Niemann-Pick type C1 disease[S]

Dietary plant stanol ester supplementation reduces peripheral symptoms in a mouse model of Niemann-Pick type C1 disease[S]

Niemann-Pick type C (NPC)1 disease is a rare genetic condition in which the function of the lysosomal cholesterol transporter NPC1 protein is impaired. Consequently, sphingolipids and cholesterol accumulate in lysosomes of all tissues, triggering a cascade of pathological events that culminate in se...

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Bibliographic Details
Main Authors: Inês Magro dos Reis, Tom Houben, Yvonne Oligschläger, Leoni Bücken, Hellen Steinbusch, David Cassiman, Dieter Lütjohann, Marit Westerterp, Jos Prickaerts, Jogchum Plat, Ronit Shiri-Sverdlov
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Journal of Lipid Research
Subjects:
inflammation
cholesterol metabolism
diet
dietary lipids
liver
atherosclerosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520435953

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http://www.sciencedirect.com/science/article/pii/S0022227520435953

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