Biological insights from multi-omic analysis of 31 genomic risk loci for adult hearing difficulty.

Age-related hearing impairment (ARHI), one of the most common medical conditions, is strongly heritable, yet its genetic causes remain largely unknown. We conducted a meta-analysis of GWAS summary statistics from multiple hearing-related traits in the UK Biobank (n = up to 330,759) and identified 31...

Full description

Bibliographic Details
Main Authors: Gurmannat Kalra, Beatrice Milon, Alex M Casella, Brian R Herb, Elizabeth Humphries, Yang Song, Kevin P Rose, Ronna Hertzano, Seth A Ament
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-09-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009025