Production of Atosiban’s Key Intermediate Pentapeptide: Synthetic Approaches to the Development of a Peptide Synthesis with Less Racemization and Simplifier Purification Process

Production of Atosiban’s Key Intermediate Pentapeptide: Synthetic Approaches to the Development of a Peptide Synthesis with Less Racemization and Simplifier Purification Process

The key intermediate NH<sub>2</sub>-Ile-Thr(Bzl)-Asn-Cys(Bzl)-Pro-COOH of Atosiban was prepared from <i>N</i>-Boc-<i>S</i>-Bzl-cysteine by the stepwise lengthening of the chain according to the repetitive <i>N</i>,<i>O</i>-bis(trimethylsily...

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Bibliographic Details
Main Authors: Chunying Ma, Yixuan Zheng, Jinwei Liu, Xiaobao Li, Wenhua Feng
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
pentapeptide intermediate
atosiban
BSA/NHS
readily performed
Online Access:https://www.mdpi.com/1420-3049/27/6/1920

Internet

https://www.mdpi.com/1420-3049/27/6/1920

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