Osmanicin, a Polyketide Alkaloid Isolated from <i>Streptomyces osmaniensis</i> CA-244599 Inhibits Elastase in Human Fibroblasts

Osmanicin, a Polyketide Alkaloid Isolated from <i>Streptomyces osmaniensis</i> CA-244599 Inhibits Elastase in Human Fibroblasts

The strain <i>Streptomyces osmaniensis</i> CA-244599 isolated from the Comoros islands was submitted to liquid-state fermentation coupled to in situ solid-phase extraction with amberlite XAD-16 resin. Elution of the trapped compounds on the resin beads by ethyl acetate afforded seven met...

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Bibliographic Details
Main Authors: Mamdouh N. Samy, Géraldine Le Goff, Philippe Lopes, Katerina Georgousaki, Sentiljana Gumeni, Celso Almeida, Ignacio González, Olga Genilloud, Ioannis Trougakos, Nikolas Fokialakis, Jamal Ouazzani
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
<i>Streptomyces osmaniensis</i>
in situ solid-phase extraction
osmanicin
alkaloids
elastase inhibition
Online Access:https://www.mdpi.com/1420-3049/24/12/2239

Internet

https://www.mdpi.com/1420-3049/24/12/2239

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