Evaluation of Integrin α<sub>v</sub>β<sub>3</sub> Expression in Murine Xenograft Models: [<sup>68</sup>Ga]Ga-DOTA-C(RGDfK) PET Study with Immunohistochemical Confirmation

Evaluation of Integrin α<sub>v</sub>β<sub>3</sub> Expression in Murine Xenograft Models: [<sup>68</sup>Ga]Ga-DOTA-C(RGDfK) PET Study with Immunohistochemical Confirmation

Tumor blood flow (TBF) is related to drug delivery and hypoxia, both of which can impact the efficacy of anti-cancer therapies. Although integrin α<sub>v</sub>β<sub>3</sub> expression is related to tumor angiogenesis, it remains unclear whether the degree of angiogenesis affe...

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Bibliographic Details
Main Authors: Kosuke Mitsuyuki, Tadashi Watabe, Sadahiro Naka, Yuwei Liu, Mitsuaki Tatsumi, Eku Shimosegawa, Hiroki Kato
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Diagnostics
Subjects:
[<sup>68</sup>Ga]Ga-DOTA-c(RGDfK)
tumor angiogenesis
tumor blood flow
small-animal positron emission tomography
C6 glioma
MIA PaCa-2
Online Access:https://www.mdpi.com/2075-4418/11/7/1295

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https://www.mdpi.com/2075-4418/11/7/1295

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