Transposon Dysregulation Modulates dWnt4 Signaling to Control Germline Stem Cell Differentiation in Drosophila.

Germline stem cell (GSC) self-renewal and differentiation are required for the sustained production of gametes. GSC differentiation in Drosophila oogenesis requires expression of the histone methyltransferase dSETDB1 by the somatic niche, however its function in this process is unknown. Here, we sho...

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Main Authors: Maitreyi Upadhyay, Yesenia Martino Cortez, SiuWah Wong-Deyrup, Leticia Tavares, Sean Schowalter, Pooja Flora, Corinne Hill, Mohamad Ali Nasrallah, Sridar Chittur, Prashanth Rangan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4809502?pdf=render