Dynamic Regulation of Transporter Expression to Increase L-Threonine Production Using L-Threonine Biosensors

The cytotoxicity of overexpressed transporters limits their application in biochemical production. To overcome this problem, we developed a feedback circuit for L-threonine production that uses a biosensor to regulate transporter expression. First, we used IPTG-induced <i>rhtA</i> regula...

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Bibliographic Details
Main Authors: Sumeng Wang, Ruxin Hao, Xin Jin, Xiaomeng Li, Qingsheng Qi, Quanfeng Liang
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Fermentation
Subjects:
Online Access:https://www.mdpi.com/2311-5637/8/6/250