Lipid accumulation impairs natural killer cell cytotoxicity and tumor control in the postoperative period

Lipid accumulation impairs natural killer cell cytotoxicity and tumor control in the postoperative period

Abstract Background Natural killer (NK) cell dysfunction following cancer surgery has been shown to promote metastases. Recent studies demonstrate an emerging role for lipids in the modulation of NK cell innate responses. However, the mechanisms involved in lipid modulation of NK cell postoperative...

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Bibliographic Details
Main Authors: Seyedeh Raheleh Niavarani, Christine Lawson, Orneala Bakos, Marie Boudaud, Cory Batenchuk, Samuel Rouleau, Lee-Hwa Tai
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
Fatty natural killer cells
Perioperative immunosuppression
Immunometabolism
Online Access:http://link.springer.com/article/10.1186/s12885-019-6045-y

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http://link.springer.com/article/10.1186/s12885-019-6045-y

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