Biphasic regulation of osteoblast development via the ERK MAPK–mTOR pathway

Biphasic regulation of osteoblast development via the ERK MAPK–mTOR pathway

Emerging evidence supports that osteogenic differentiation of skeletal progenitors is a key determinant of overall bone formation and bone mass. Despite extensive studies showing the function of mitogen-activated protein kinases (MAPKs) in osteoblast differentiation, none of these studies show in vi...

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Bibliographic Details
Main Authors: Jung-Min Kim, Yeon-Suk Yang, Jaehyoung Hong, Sachin Chaugule, Hyonho Chun, Marjolein CH van der Meulen, Ren Xu, Matthew B Greenblatt, Jae-hyuck Shim
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-08-01
Series:eLife
Subjects:
MEK
ERK
mTOR
osteoblast
Online Access:https://elifesciences.org/articles/78069

Internet

https://elifesciences.org/articles/78069

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