Understanding CRY2 interactions for optical control of intracellular signaling

Understanding CRY2 interactions for optical control of intracellular signaling

Cryptochrome 2 (CRY2) can form light-regulated CRY2-CRY2 homo-oligomers or CRY2-CIB1 hetero-dimers, but modulating these interactions is difficult owing to the lack of interaction mechanism. Here the authors identify the interactions facilitating homo-oligomers and introduce mutations to create low...

Full description

Bibliographic Details
Main Authors: Liting Duan, Jen Hope, Qunxiang Ong, Hsin-Ya Lou, Namdoo Kim, Comfrey McCarthy, Victor Acero, Michael Z. Lin, Bianxiao Cui
Format: Article
Language:English
Published: Nature Portfolio 2017-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-00648-8

Internet

https://doi.org/10.1038/s41467-017-00648-8

Similar Items