Alarming and Calming: Opposing Roles of S100A8/S100A9 Dimers and Tetramers on Monocytes

Alarming and Calming: Opposing Roles of S100A8/S100A9 Dimers and Tetramers on Monocytes

Abstract Mechanisms keeping leukocytes distant of local inflammatory processes in a resting state despite systemic release of inflammatory triggers are a pivotal requirement for avoidance of overwhelming inflammation but are ill defined. Dimers of the alarmin S100A8/S100A9 activate Toll‐like recepto...

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Bibliographic Details
Main Authors: Antonella Russo, Hendrik Schürmann, Matthias Brandt, Katja Scholz, Anna Livia L. Matos, David Grill, Julian Revenstorff, Maximilian Rembrink, Meike von Wulffen, Lena Fischer‐Riepe, Peter J. Hanley, Hans Häcker, Monika Prünster, Francisco Sánchez‐Madrid, Sven Hermann, Luisa Klotz, Volker Gerke, Timo Betz, Thomas Vogl, Johannes Roth
Format: Article
Language:English
Published: Wiley 2022-12-01
Series:Advanced Science
Subjects:
alarmin
calprotectin
CD69
MRP8/MRP14
migration
S100A8/S100A9 tetramer
Online Access:https://doi.org/10.1002/advs.202201505

Internet

https://doi.org/10.1002/advs.202201505

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