Automated visualization of rule-based models.

Frameworks such as BioNetGen, Kappa and Simmune use "reaction rules" to specify biochemical interactions compactly, where each rule specifies a mechanism such as binding or phosphorylation and its structural requirements. Current rule-based models of signaling pathways have tens to hundred...

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Bibliographic Details
Main Authors: John Arul Prakash Sekar, Jose-Juan Tapia, James R Faeder
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC5703574?pdf=render