Automated visualization of rule-based models.
Frameworks such as BioNetGen, Kappa and Simmune use "reaction rules" to specify biochemical interactions compactly, where each rule specifies a mechanism such as binding or phosphorylation and its structural requirements. Current rule-based models of signaling pathways have tens to hundred...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2017-11-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC5703574?pdf=render |