Risk Factors Associated with Adverse Events Leading to Methotrexate Withdrawal in Elderly Rheumatoid Arthritis Patients: A Retrospective Cohort Study

Risk Factors Associated with Adverse Events Leading to Methotrexate Withdrawal in Elderly Rheumatoid Arthritis Patients: A Retrospective Cohort Study

<b>Background:</b> Rheumatoid arthritis (RA) in elderly population represents a challenge for physicians in terms of therapeutic management. Methotrexate (MTX) is the first-line treatment among conventional synthetic-disease-modifying anti-rheumatic drugs (cs-DMARDs); however, it is ofte...

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Main Authors: Felipe Alexis Avalos-Salgado, Laura Gonzalez-Lopez, Sergio Gonzalez-Vazquez, Juan Manuel Ponce-Guarneros, Aline Priscilla Santiago-Garcia, Edna Lizeth Amaya-Cabrera, Reynaldo Arellano-Cervantes, J. Ahuixotl Gutiérrez-Aceves, Miriam Fabiola Alcaraz-Lopez, Cesar Arturo Nava-Valdivia, Fabiola Gonzalez-Ponce, Norma Alejandra Rodriguez-Jimenez, Miguel Angel Macias-Islas, Edgar Ricardo Valdivia-Tangarife, Ana Miriam Saldaña-Cruz, Ernesto German Cardona-Muñoz, Jorge Ivan Gamez-Nava
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Journal of Clinical Medicine
Subjects:
rheumatoid arthritis in elderly
methotrexate
adverse events
withdrawals
treatment persistence
retrospective cohort studies
Online Access:https://www.mdpi.com/2077-0383/13/7/1863

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https://www.mdpi.com/2077-0383/13/7/1863

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