Disrupted presynaptic nectin1-based neuronal adhesion in the entorhinal-hippocampal circuit contributes to early-life stress-induced memory deficits
Abstract The cell adhesion molecule nectin3 and its presynaptic partner nectin1 have been linked to early-life stress-related cognitive disorders, but how the nectin1-nectin3 system contributes to stress-induced neuronal, circuit, and cognitive abnormalities remains to be studied. Here we show that...
Main Authors: | Chen Wu, Qian Gong, Xue Xu, Ping Fang, Chi Wang, Jing-Ying Yu, Xing-Xing Wang, San-Hua Fang, Wen-Juan Chen, Hui-Fang Lou, Yu-Hui Liu, Liang Wang, Yi-Jun Liu, Wei Chen, Xiao-Dong Wang |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2022-04-01
|
Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-022-01908-y |
Similar Items
-
Kindling alters entorhinal cortex-hippocampal interaction by increased efficacy of presynaptic GABAb autoreceptors in layer III of the entorhinal cortex
by: Tengis Gloveli, et al.
Published: (2003-08-01) -
Human P301L-mutant tau expression in mouse entorhinal-hippocampal network causes tau aggregation and presynaptic pathology but no cognitive deficits.
by: Julie A Harris, et al.
Published: (2012-01-01) -
A Hippocampal-Entorhinal Cortex Neuronal Network for Dynamical Mechanisms of Epileptic Seizure
by: Ying Yu, et al.
Published: (2023-01-01) -
Ketamine evoked disruption of entorhinal and hippocampal spatial maps
by: Francis Kei Masuda, et al.
Published: (2023-10-01) -
Entorhinal–hippocampal neuronal circuits bridge temporally discontiguous events
by: Kitamura, Takashi, et al.
Published: (2017)