Role of AmpG in the resistance to β-lactam agents, including cephalosporins and carbapenems: candidate for a novel antimicrobial target

Abstract Background A complex cascade of genes, enzymes, and transcription factors regulates AmpC β-lactamase overexpression. We investigated the network of AmpC β-lactamase overexpression in Klebsiella aerogenes and identified the role of AmpG in resistance to β-lactam agents, including cephalospor...

Full description

Bibliographic Details
Main Authors: Roshan D’Souza, Le Phuong Nguyen, Naina A. Pinto, Hyunsook Lee, Thao Nguyen Vu, Hoyoung Kim, Hyun Soo Cho, Dongeun Yong
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Online Access:https://doi.org/10.1186/s12941-021-00446-7