High-throughput mechanical phenotyping and transcriptomics of single cells
Abstract The molecular system regulating cellular mechanical properties remains unexplored at single-cell resolution mainly due to a limited ability to combine mechanophenotyping with unbiased transcriptional screening. Here, we describe an electroporation-based lipid-bilayer assay for cell surface...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-05-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-48088-5 |