Silk/Fibroin Microcarriers for Mesenchymal Stem Cell Delivery: Optimization of Cell Seeding by the Design of Experiment

Silk/Fibroin Microcarriers for Mesenchymal Stem Cell Delivery: Optimization of Cell Seeding by the Design of Experiment

In this methodological paper, lyophilized fibroin-coated alginate microcarriers (LFAMs) proposed as mesenchymal stem cells (MSCs) delivery systems and optimal MSCs seeding conditions for cell adhesion rate and cell arrangement, was defined by a Design of Experiment (DoE) approach. Cells were co-incu...

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Bibliographic Details
Main Authors: Carlotta Perucca Orfei, Giuseppe Talò, Marco Viganò, Sara Perteghella, Gaia Lugano, Francesca Fabro Fontana, Enrico Ragni, Alessandra Colombini, Paola De Luca, Matteo Moretti, Maria Luisa Torre, Laura de Girolamo
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:Pharmaceutics
Subjects:
mesenchymal stem cells
microcarrier
design of experiment
cell delivery
silk fibroin
alginate
one-step clinical procedure
Online Access:https://www.mdpi.com/1999-4923/10/4/200

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https://www.mdpi.com/1999-4923/10/4/200

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