Multidirectional characterization of cellular composition and spatial architecture in human multiple primary lung cancers

Multidirectional characterization of cellular composition and spatial architecture in human multiple primary lung cancers

Abstract Multiple primary lung cancers (MPLCs) pose diagnostic and therapeutic challenges in clinic. Here, we orchestrated the cellular and spatial architecture of MPLCs by combining single-cell RNA-sequencing and spatial transcriptomics. Notably, we identified a previously undescribed sub-populatio...

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Bibliographic Details
Main Authors: Yawei Wang, Di Chen, Yu Liu, Daiwang Shi, Chao Duan, Jinghan Li, Xiang Shi, Yong Zhang, Zhanwu Yu, Nan Sun, Wei Wang, Yegang Ma, Xiaohan Xu, Wuxiyar Otkur, Xiaolong Liu, Tian Xia, Huan Qi, Hai-long Piao, Hong-Xu Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05992-w

Internet

https://doi.org/10.1038/s41419-023-05992-w

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