The proportion of myeloid-derived suppressor cells in the spleen is related to the severity of the clinical course and tissue damage extent in a murine model of multiple sclerosis

The proportion of myeloid-derived suppressor cells in the spleen is related to the severity of the clinical course and tissue damage extent in a murine model of multiple sclerosis

Multiple Sclerosis (MS) is the second cause of paraplegia among young adults, after all types of CNS traumatic lesions. In its most frequent relapsing-remitting form, the severity of the disease course is very heterogeneous, and its reliable evaluation remains a key issue for clinicians. Myeloid-Der...

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Bibliographic Details
Main Authors: Carolina Melero-Jerez, Aitana Alonso-Gómez, Esther Moñivas, Rafael Lebrón-Galán, Isabel Machín-Díaz, Fernando de Castro, Diego Clemente
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Neurobiology of Disease
Subjects:
EAE
MDSCs
Biomarkers
Disease severity
Demyelination
CNS damage
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996120301443

Internet

http://www.sciencedirect.com/science/article/pii/S0969996120301443

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