Implication of SPARC in the modulation of the extracellular matrix and mitochondrial function in muscle cells.

Secreted protein, acidic and rich in cysteine (SPARC) is differentially associated with cell proliferation and extracellular matrix (ECM) assembly. We show here the effect of exogenous SPARC inhibition/induction on ECM and mitochondrial proteins expression and on the differentiation of C2C12 cells....

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Bibliographic Details
Main Authors: Aicha Melouane, Antoine Carbonell, Mayumi Yoshioka, Jack Puymirat, Jonny St-Amand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5805355?pdf=render