Melatonin delivered in solid lipid nanoparticles ameliorated its neuroprotective effects in cerebral ischemia

Melatonin delivered in solid lipid nanoparticles ameliorated its neuroprotective effects in cerebral ischemia

The current study explores the potential of melatonin (MLT)-loaded solid lipid nanoparticles (MLT-SLNs) for better neuroprotective effects in ischemic stroke. MLT-SLNs were prepared using lipid matrix of palmityl alcohol with a mixture of surfactants (Tween 40, Span 40, Myrj 52) for stabilizing the...

Full description

Bibliographic Details
Main Authors: Saba Sohail, Fawad Ali Shah, Shahiq uz Zaman, Ali H. Almari, Imran Malik, Saifoor Ahmad Khan, Abir Abdullah Alamro, Alam Zeb, Fakhar ud Din
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Heliyon
Subjects:
Melatonin
Solid lipid nanoparticles
Ischemic stroke
Sustained release
Brain delivery
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023069876

Internet

http://www.sciencedirect.com/science/article/pii/S2405844023069876

Similar Items