Theacrine alleviates sepsis-induced acute kidney injury by repressing the activation of NLRP3/Caspase-1 inflammasome
Acute kidney injury (AKI) is a frequent and serious complication of sepsis, which results in a rapid decline of kidney function. Currently, there are no curative therapies for AKI. Theacrine is a purine alkaloid and exerts significant role in regulating inflammation, oxidative stress, and mood eleva...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2022-10-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/14109.pdf |