Age-associated genes in human mammary gland drive human breast cancer progression

Age-associated genes in human mammary gland drive human breast cancer progression

Abstract Background Aging is a comorbidity of breast cancer suggesting that aging-associated transcriptome changes may promote breast cancer progression. However, the mechanism underlying the age effect on breast cancer remains poorly understood. Method We analyzed transcriptomics of the matched nor...

Full description

Bibliographic Details
Main Authors: Xiang Gu, Bingzhi Wang, Haiyan Zhu, You Zhou, Aaron M. Horning, Tim H-M Huang, Yidong Chen, Peter Houghton, Zhao Lai, Joel E. Michalek, Lu-Zhe Sun
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Breast Cancer Research
Subjects:
Aging
Breast cancer
Transcriptomics
Gene expression
Relapse-free survival
Tumor progression
Online Access:http://link.springer.com/article/10.1186/s13058-020-01299-2

Internet

http://link.springer.com/article/10.1186/s13058-020-01299-2

Similar Items