Genome-wide investigation of DNA methylation marks associated with FV Leiden mutation.

Genome-wide investigation of DNA methylation marks associated with FV Leiden mutation.

In order to investigate whether DNA methylation marks could contribute to the incomplete penetrance of the FV Leiden mutation, a major genetic risk factor for venous thrombosis (VT), we measured genome-wide DNA methylation levels in peripheral blood samples of 98 VT patients carrying the mutation an...

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Bibliographic Details
Main Authors: Dylan Aïssi, Jessica Dennis, Martin Ladouceur, Vinh Truong, Nora Zwingerman, Ares Rocanin-Arjo, Marine Germain, Tara A Paton, Pierre-Emmanuel Morange, France Gagnon, David-Alexandre Trégouët
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4179266?pdf=render

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http://europepmc.org/articles/PMC4179266?pdf=render

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