Sex-Dependent Altered Expression of Cannabinoid Signaling in Hippocampal Astrocytes of the Triple Transgenic Mouse Model of Alzheimer’s Disease: Implications for Controlling Astroglial Activity

Sex-Dependent Altered Expression of Cannabinoid Signaling in Hippocampal Astrocytes of the Triple Transgenic Mouse Model of Alzheimer’s Disease: Implications for Controlling Astroglial Activity

Alzheimer’s disease (AD) is a common neurodegenerative disease. In AD-associated neuroinflammation, astrocytes play a key role, finding glial activation both in patients and in animal models. The endocannabinoid system (ECS) is a neurolipid signaling system with anti-inflammatory and neuroprotective...

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Bibliographic Details
Main Authors: Beatriz Pacheco-Sánchez, Rubén Tovar, Meriem Ben Rabaa, Lourdes Sánchez-Salido, Antonio Vargas, Juan Suárez, Fernando Rodríguez de Fonseca, Patricia Rivera
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
3×Tg-AD-AD mice
Alzheimer’s disease
astrocytes
hippocampus
endocannabinoid system
Online Access:https://www.mdpi.com/1422-0067/24/16/12598

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https://www.mdpi.com/1422-0067/24/16/12598

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