T cell immunity as a tool for studying epigenetic regulation of cellular differentiation

Cellular differentiation is regulated by the strict spatial and temporal control of gene expression. This is achieved, in part, by regulating changes in histone post-translational modifications (PTMs) and DNA methylation that in-turn, impact transcriptional activity. Further, histone PTMs and DNA me...

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Bibliographic Details
Main Authors: Brendan Edward Russ, Julia E Prier, Sudha eRao, Stephen J Turner
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-11-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00218/full