Anti-Metastatic Properties of a Marine Bacterial Exopolysaccharide-Based Derivative Designed to Mimic Glycosaminoglycans

Anti-Metastatic Properties of a Marine Bacterial Exopolysaccharide-Based Derivative Designed to Mimic Glycosaminoglycans

Osteosarcoma is the most frequent malignant primary bone tumor characterized by a high potency to form lung metastases. In this study, the effect of three oversulfated low molecular weight marine bacterial exopolysaccharides (OS-EPS) with different molecular weights (4, 8 and 15 kDa) were first eval...

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Bibliographic Details
Main Authors: Dominique Heymann, Carmen Ruiz-Velasco, Julie Chesneau, Jacqueline Ratiskol, Corinne Sinquin, Sylvia Colliec-Jouault
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Molecules
Subjects:
exopolysaccharides
glycosaminoglycan
heparin-like
derivatives
sulfation
bone metabolism
bone remodeling
lung mestatases
osteosarcoma
Online Access:http://www.mdpi.com/1420-3049/21/3/309

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http://www.mdpi.com/1420-3049/21/3/309

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