Pharmacological inhibition of Src family kinases attenuates hyperuricemic nephropathy

Pharmacological inhibition of Src family kinases attenuates hyperuricemic nephropathy

Hyperuricemia is an independent risk factor for chronic kidney disease and contributes to renal fibrosis. This study aims to investigate the effect of Src family kinase (SFK) inhibition on the development of hyperuricemic nephropathy (HN) and the mechanisms involved. In a rat model of HN, feeding ra...

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Bibliographic Details
Main Authors: Chongxiang Xiong, Jin Deng, Xin Wang, Qidi Hou, Shougang Zhuang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Pharmacology
Subjects:
hyperuricemia
hyperuricemic nephropathy
Src family kinases
Src
fibrosis
kidney
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1352730/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2024.1352730/full

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