Identification and Characterization of Zika Virus NS5 Methyltransferase Inhibitors

Identification and Characterization of Zika Virus NS5 Methyltransferase Inhibitors

The recurring outbreak of Zika virus (ZIKV) worldwide makes an emergent demand for novel, safe and efficacious anti-ZIKV agents. ZIKV non-structural protein 5 (NS5) methyltransferase (MTase), which is essential for viral replication, is regarded as a potential drug target. In our study, a luminescen...

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Bibliographic Details
Main Authors: Weibao Song, Hongjuan Zhang, Yu Zhang, Ying Chen, Yuan Lin, Yanxing Han, Jiandong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Zika virus
NS5
methyltransferase
inhibitors
theaflavin
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.665379/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.665379/full

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