Voltage-gated ion channels mediate the electrotaxis of glioblastoma cells in a hybrid PMMA/PDMS microdevice

Transformed astrocytes in the most aggressive form cause glioblastoma, the most common cancer in the central nervous system with high mortality. The physiological electric field by neuronal local field potentials and tissue polarity may guide the infiltration of glioblastoma cells through the electr...

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Bibliographic Details
Main Authors: Hsieh-Fu Tsai, Camilo IJspeert, Amy Q. Shen
Format: Article
Language:English
Published: AIP Publishing LLC 2020-09-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0004893