Voltage-gated ion channels mediate the electrotaxis of glioblastoma cells in a hybrid PMMA/PDMS microdevice
Transformed astrocytes in the most aggressive form cause glioblastoma, the most common cancer in the central nervous system with high mortality. The physiological electric field by neuronal local field potentials and tissue polarity may guide the infiltration of glioblastoma cells through the electr...
Main Authors: | Hsieh-Fu Tsai, Camilo IJspeert, Amy Q. Shen |
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Format: | Article |
Language: | English |
Published: |
AIP Publishing LLC
2020-09-01
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Series: | APL Bioengineering |
Online Access: | http://dx.doi.org/10.1063/5.0004893 |
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