Influence of placental exosomes from early onset preeclampsia women umbilical cord plasma on human umbilical vein endothelial cells

Influence of placental exosomes from early onset preeclampsia women umbilical cord plasma on human umbilical vein endothelial cells

BackgroundEarly onset preeclampsia (EOSP, PE) is characterized by hypertension, proteinuria, and endothelial dysfunction. Oxidative stress-induced trophoblast dysfunction is a major pathology in PE. Placental exosomes are extracellular vesicles that are involved in “mother-placenta-foetal communicat...

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Bibliographic Details
Main Authors: Mengqi Gu, Fengyuan Zhang, Xiaotong Jiang, Pengzheng Chen, Shuting Wan, Qingfeng Lv, Yuan Lu, Qian Zhou, Yanyun Wang, Lei Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
placental exosomes
HUVECs
hypoxia/reoxygenation
permeability of the endothelial monolayer
early onset preeclampsia
pregnancy
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2022.1061340/full

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https://www.frontiersin.org/articles/10.3389/fcvm.2022.1061340/full

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