PDK4 inhibits osteoarthritis progression by activating the PPAR pathway
Abstract Background Osteoarthritis (OA) is a degenerative joint disease caused by the deterioration of cartilage. However, the underlying mechanisms of OA pathogenesis remain elusive. Methods Hub genes were screened by bioinformatics analysis based on the GSE114007 and GSE169077 datasets. The Spragu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-02-01
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Series: | Journal of Orthopaedic Surgery and Research |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13018-024-04583-5 |