Cyclooxygenase-2 Facilitates Newcastle Disease Virus Proliferation and Is as a Target for Canthin-6-One Antiviral Activity

Cyclooxygenase-2 Facilitates Newcastle Disease Virus Proliferation and Is as a Target for Canthin-6-One Antiviral Activity

Cyclooxygenase-2 (COX-2), one of the mediators of inflammation in response to viral infection, plays an important role in host antiviral defense system. But its role in Newcastle disease virus (NDV) proliferation process remains unclear. This study revealed that inhibition of COX-2 could benefit NDV...

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Bibliographic Details
Main Authors: Chongyang Wang, Ting Wang, Ruochen Hu, Jiangkun Dai, Haijin Liu, Na Li, Uwe Schneider, Zengqi Yang, Junru Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Microbiology
Subjects:
cyclooxygenase-2
prostaglandin E2
Newcastle disease virus
canthin-6-one
antiviral
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00987/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00987/full

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