Synergistic bactericidal effects of phage-enhanced antibiotic therapy against MRSA biofilms

Synergistic bactericidal effects of phage-enhanced antibiotic therapy against MRSA biofilms

ABSTRACTMethicillin-resistant Staphylococcus aureus (MRSA) causes biofilm-related medical device infections. Phage-antibiotic combinations offer potential therapy due to proven in vitro antibiofilm efficacy. We evaluated phage-antibiotic synergy against biofilms using modified checkerboard and 24-h...

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Bibliographic Details
Main Authors: Ashlan J. Kunz Coyne, Kyle Stamper, Callan Bleick, Razieh Kebriaei, Susan M. Lehman, Michael J. Rybak
Format: Article
Language:English
Published: American Society for Microbiology 2024-04-01
Series:Microbiology Spectrum
Subjects:
MRSA
biofilm
bacteriophage
daptomycin
ceftaroline
bacterial synergy
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03212-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03212-23

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