Single mutation at a highly conserved region of chloramphenicol acetyltransferase enables isobutyl acetate production directly from cellulose by Clostridium thermocellum at elevated temperatures

Single mutation at a highly conserved region of chloramphenicol acetyltransferase enables isobutyl acetate production directly from cellulose by Clostridium thermocellum at elevated temperatures

Abstract Background Esters are versatile chemicals and potential drop-in biofuels. To develop a sustainable production platform, microbial ester biosynthesis using alcohol acetyltransferases (AATs) has been studied for decades. Volatility of esters endows high-temperature fermentation with advantage...

Full description

Bibliographic Details
Main Authors: Hyeongmin Seo, Jong-Won Lee, Sergio Garcia, Cong T. Trinh
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Biotechnology for Biofuels
Subjects:
Alcohol acetyltransferase
Thermostability
Chloramphenicol acetyltransferase
Isobutyl acetate
Esters
Consolidated bioprocessing
Online Access:http://link.springer.com/article/10.1186/s13068-019-1583-8

Internet

http://link.springer.com/article/10.1186/s13068-019-1583-8

Similar Items