Acute myeloid leukemia in SRP54‐mutated congenital neutropenia

Acute myeloid leukemia in SRP54‐mutated congenital neutropenia

Abstract SRP54 mutations have recently been implicated in congenital neutropenia (CN) and the in‐frame deletion, p.Thr117del, is the most common pathogenic mutation reported. The largest study of SRP54‐mutated CN to‐date followed 23 patients for a median of 15 years. No patients developed a hematolo...

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Bibliographic Details
Main Authors: Anthony Sabulski, David D. Grier, Kasiani C. Myers, Stella M. Davies, Jeremy D. Rubinstein
Format: Article
Language:English
Published: Wiley 2022-05-01
Series:eJHaem
Subjects:
congenital neutropenia
pediatric leukemia
hematopoietic cell transplant
Online Access:https://doi.org/10.1002/jha2.413

Internet

https://doi.org/10.1002/jha2.413

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