Brain-protective mechanisms of autophagy associated circRNAs: Kick starting self-cleaning mode in brain cells via circRNAs as a potential therapeutic approach for neurodegenerative diseases

Brain-protective mechanisms of autophagy associated circRNAs: Kick starting self-cleaning mode in brain cells via circRNAs as a potential therapeutic approach for neurodegenerative diseases

Altered autophagy is a hallmark of neurodegeneration but how autophagy is regulated in the brain and dysfunctional autophagy leads to neuronal death has remained cryptic. Being a key cellular waste-recycling and housekeeping system, autophagy is implicated in a range of brain disorders and altering...

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Bibliographic Details
Main Authors: Rabea Basri, Faryal Mehwish Awan, Burton B. Yang, Usman Ayub Awan, Ayesha Obaid, Anam Naz, Aqsa Ikram, Suliman Khan, Ijaz ul Haq, Sadiq Noor Khan, Muslim Bin Aqeel
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Molecular Neuroscience
Subjects:
circRNAs
autophagy
neurodegeneration
nervous system
therapeutics
Online Access:https://www.frontiersin.org/articles/10.3389/fnmol.2022.1078441/full

Internet

https://www.frontiersin.org/articles/10.3389/fnmol.2022.1078441/full

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