Molecular Dynamics Simulations Study of the Interactions between Human Dipeptidyl-Peptidase III and Two Substrates

Molecular Dynamics Simulations Study of the Interactions between Human Dipeptidyl-Peptidase III and Two Substrates

Human dipeptidyl-peptidase III (hDPP III) is capable of specifically cleaving dipeptides from the N-terminal of small peptides with biological activity such as angiotensin II (Ang II, DRVYIHPF), and participates in blood pressure regulation, pain modulation, and the development of cancers in human b...

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Bibliographic Details
Main Authors: Shitao Zhang, Shuai Lv, Xueqi Fu, Lu Han, Weiwei Han, Wannan Li
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
human dipeptidyl-peptidase III
substrate
molecular dynamics simulations
conformational changes
Online Access:https://www.mdpi.com/1420-3049/26/21/6492

Internet

https://www.mdpi.com/1420-3049/26/21/6492

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