The role of the globular heads of the C1q receptor in TcdA-induced human colonic epithelial cell apoptosis via a mitochondria-dependent pathway

The role of the globular heads of the C1q receptor in TcdA-induced human colonic epithelial cell apoptosis via a mitochondria-dependent pathway

Abstract Background Clostridioides (formerly Clostridium) difficile infection is the leading cause of antibiotic-associated colitis. Studies have demonstrated that C. difficile toxin A (TcdA) can cause apoptosis of many human cell types. The purpose of this study was to investigate the relationships...

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Bibliographic Details
Main Authors: Jinhua Liang, Yongzhong Ning, Li Dong, Xiufeng Ma, Shu Li, Heran Yang, Qi Li, Ling Chen, Lingjuan Gao, Yanmin Xu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:BMC Microbiology
Subjects:
Clostridium difficile
TcdA
gC1qR
Mitochondrial function, apoptosis
Online Access:http://link.springer.com/article/10.1186/s12866-020-01958-6

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http://link.springer.com/article/10.1186/s12866-020-01958-6

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