Genetic and immune microenvironment characterization of HER2‐positive gastric cancer: Their association with response to trastuzumab‐based treatment

Genetic and immune microenvironment characterization of HER2‐positive gastric cancer: Their association with response to trastuzumab‐based treatment

Abstract Background We aimed to determine the molecular and immune microenvironment characteristics of HER2‐positive gastric cancer (GC) related to the patient's response to first‐line trastuzumab‐based treatment. Methods Eighty‐three cases of HER2‐positive advanced gastric adenocarcinoma patie...

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Bibliographic Details
Main Authors: Hyun Jung Kwon, Yujun Park, Soo Kyung Nam, Enoch Kang, Ka‐Kyung Kim, Inhae Jeong, Yoonjin Kwak, Jeesun Yoon, Tae‐Yong Kim, Keun‐Wook Lee, Do‐Youn Oh, Seock‐Ah Im, Seong‐Ho Kong, Do Joong Park, Hyuk‐Joon Lee, Hyung‐Ho Kim, Han‐Kwang Yang, Hye Seung Lee
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Cancer Medicine
Subjects:
cell cycle
HER2‐positive gastric cancer
NK cell
PD‐L1
trastuzumab
Online Access:https://doi.org/10.1002/cam4.5769

Internet

https://doi.org/10.1002/cam4.5769

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