Facile Synthesis of Oleanolic Acid Monoglycosides and Diglycosides

Facile Synthesis of Oleanolic Acid Monoglycosides and Diglycosides

Oleanolic acid and its glycosides are important natural products, possessing various attractive biological activities such as antitumor, antivirus and anti-inflammatory properties. In the present work, fifteen oleanolic acid saponins bearing various saccharide moieties, including 3-monoglycoside, 28...

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Bibliographic Details
Main Authors: Mao-Sheng Cheng, Yang Liu, Jiao Liu, Mao-Cai Yan, Yu Sha
Format: Article
Language:English
Published: MDPI AG 2008-07-01
Series:Molecules
Subjects:
Oleanolic acid and its glycosides are important natural products
possessing various attractive biological activities such as antitumor
antivirus and anti-inflammatory properties. In the present work
fifteen oleanolic acid saponins bearing various saccharide moieties
including 3-monoglycoside
28-monoglycoside and 3
28-diglycoside
were easily synthesized in high yields. Benzyl was chosen as the protective group for the COOH(28) group
instead of commonly used methyl and allyl
to avoid diffi
Online Access:http://www.mdpi.com/1420-3049/13/7/1472/

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