Maleic Acid as a Co-Former for Pharmaceutically Active GABA Derivatives: Mechanochemistry or Solvent Crystallization?

In this study, we compare the mechanochemical and classical solvent crystallization methods for forming maleates of GABA and its pharmaceutically active derivatives: Pregabalin, Gabapentin, Phenibut, and Baclofen. Common characterization techniques, like powder and single crystal X-ray diffraction,...

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Bibliographic Details
Main Authors: Daniel Komisarek, Ebru Taskiran, Vera Vasylyeva
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Materials
Subjects:
Online Access:https://www.mdpi.com/1996-1944/16/6/2242